Magnesium Sulfate

*CNS depressant
*Decreases the amount of acetylcholine which decreases neuromuscular transmission

Therapeutic level 4.8-9.6 mg/dL

Toxicity

Blood Pressure will be low

Urine output will be low

Respirations will be low

Patellar reflex absent

Antidote Calcium Gluconate

Interventions

Monitor Vital Signs (RR & BP)
Draw Magnesium levels per order Monitor FHR
Head to Toe Assessment (DTR, LOC) Usually on for 24 hours postpartum

Contraindications

▪ Renal disease
▪ Heart disease
▪ Myasthenia Gravis

Side Effects

  • Decreased respirations
  • Nausea & Vomiting Headache
  • Altered LOC/confusion
  • Drowsiness
  • Sweaty Flushing
Two Main uses:

Preterm Labor
Loading dose 4-6 grams in 100 mL over 20 minutes
Maintenance dose 1-4grams/hour

Preeclampsia
Loading dose 6 Grams over 20 minutes Maintenance 2 grams/hour

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