Prothrombin is a protein from liver
One of many clotting factors
Evaluates factors V, VII, X, prothrombin and fibrinogen extrinsic coagulation system
Normal range: 10 to 14 seconds
If on Warfarin: 1-2.5 X the normal
Uses for PT
- 1. Monitor response to anticoagulant
- 2. Diagnosis liver problems
- 3. Assess blood’s ability to clot before surgery
Things that can alter the results: Antihistamines, Steroids, Antibiotics, & Digoxin
INR (International Normalized Ratio)
Normal value 1.1
Warfarin Therapy 2-3
Purpose: To evaluate the effectiveness of oral anticoagulant therapy
| Increased Levels Decreased Levels | |
| DIC Risk for blood clot Cirrhosis Hepatitis Warfarin Vitamin K deficiency |
*Test should be done once a month to twice a week
Nursing Interventions: Call doctor, give vitamin K, doctor may adjust patient’s warfarin