Anaphylaxis

Anaphylaxis is a severe, potentially life-threatening allergic reaction.

The immune system produces antibodies to defend against foreign substances. In anaphylaxis the immune system overreacts.

Signs & Symptoms

  • Hypotension
  • Constriction of the airways
  • A weak and rapid pulse
  • Dizziness
  • Hives/itchy
  • Shortness of breath

Starts 5-30 minutes after exposure
Biphasic-2nd wave of symptoms. Can be hours to days later

Common Triggers

  • Peanuts
  • Shellfish
  • Penicillin
  • Pollen
  • Stings (bees, wasps)
  • Latex

Some people are so sensitive that even the smell or cross contamination can trigger a reaction

Treatment

  • EpiPen-Epinephrine is the most effective treatment for anaphylaxis, and the shot should be given right away
    • Pregnant patients should lie on their left side
    • Trendelenburg Position (increase blood pressure)
    • IM or SUBQ
  • IV antihistamines and cortisone
  • Albuterol
  • Oxygen
  • Intubation
  • Tracheostomy

Complications

  • brain damage
  • kidney failure
  • arrhythmias
  • death

Prevention

  • Wear a medical alert bracelet
  • Keep an emergency kit
  • Read labels
  • Use caution around insects
  • Get allergy tested

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